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Health & Longevity

Supplements

5-HTP

Name: 5-HTP
Brand: Peptalon
SKU: SU-0003-03-100
Availability: InStock
Rating: 4.8 (127 reviews)

Supports serotonion synthesis for better mood, sleep and appetite control.

From AED 100.00

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Key Ingredients

5-Hydroxytryptophan

Relieve Stress

Sleep Support

Promote Relaxation

Controls Appetite

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

5-HTP is a natural serotonin precursor extracted from the seeds of Griffonia simplicifolia. It helps support mood balance, reduce anxiety, and promote restful sleep by naturally increasing serotonin levels in the brain.

Scientific Background

5-HTP (5-Hydroxytryptophan) is a naturally occurring amino acid and metabolic intermediate in the biosynthesis of serotonin. It is derived from the seeds of Griffonia simplicifolia and has been widely studied for its role in mood regulation, appetite control, and sleep quality. Once ingested, 5-HTP crosses the blood-brain barrier and is rapidly converted to serotonin, influencing emotional balance and circadian rhythm (Birdsall, 1998). Clinical research has shown that 5-HTP supplementation may support individuals with mild depressive symptoms, stress-related cravings, or disrupted sleep patterns (Shaw et al., 2002). Its non-stimulant profile makes it especially suitable for evening use or as part of a holistic approach to serotonin restoration.

References

Birdsall, T. C. (1998). 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Alternative Medicine Review, 3(4), 271–280. https://doi.org/10.1177/147323009803600103
Shaw, K., Turner, J., & Del Mar, C. (2002). Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database of Systematic Reviews, (1), CD003198. https://doi.org/10.1002/14651858.CD003198

Usage Instructions

Take 5-HTP on an empty stomach for optimal absorption.
It is best taken 30–60 minutes before bedtime to promote restful sleep or earlier in the day to support mood and anxiety relief.
Avoid taking it alongside high-protein meals, which may reduce its effectiveness.

Dosage Information

For mood support:

50–100 mg, 1–2× daily

For sleep enhancement:

100–200 mg before bed

For appetite control:

100 mg 30 minutes before meals

Do not exceed 300 mg per day without medical guidance

Use for 6–12 weeks, then reassess or take a short break

Important Warnings

Do not combine with SSRIs, MAOIs, or other antidepressants without medical supervision
Avoid during pregnancy or breastfeeding
Possible side effects: nausea, vivid dreams, or drowsiness
Start with the lowest effective dose to assess tolerance
Not recommended for individuals with bipolar disorder or serotonin syndrome history

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From Mood to Metabolism: How 5-HTP Helps You Stay Balanced

Ever felt like your mood is on a rollercoaster, your cravings are out of control, or you just can’t seem to fall asleep — even when you’re exhausted? ...

Take 5-HTP on an empty stomach for optimal absorption.
It is best taken 30–60 minutes before bedtime to promote restful sleep or earlier in the day to support mood and anxiety relief.
Avoid taking it alongside high-protein meals, which may reduce its effectiveness.

Dosage Information

For mood support:

50–100 mg, 1–2× daily

For sleep enhancement:

100–200 mg before bed

For appetite control:

100 mg 30 minutes before meals

Do not exceed 300 mg per day without medical guidance

Use for 6–12 weeks, then reassess or take a short break

Important Warnings

Do not combine with SSRIs, MAOIs, or other antidepressants without medical supervision
Avoid during pregnancy or breastfeeding
Possible side effects: nausea, vivid dreams, or drowsiness
Start with the lowest effective dose to assess tolerance
Not recommended for individuals with bipolar disorder or serotonin syndrome history

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5-HTP