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Peptides Line

CJC 1295

Name: CJC 1295
Brand: Peptalon
SKU: PE-0041-01-5
Availability: InStock
Rating: 4.8 (127 reviews)

CJC-1295 without DAC is a fast-acting Growth Hormone Releasing Hormone (GHRH) analog that stimulates natural GH secretion in short, controlled pulses

From AED 190.00

format:

Key Ingredients

CJC-1295 without Drug Affinity Complex

Boosts Recovery

Fat Burning Support

Growth Hormone Optimization

Supports Healthy Aging

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

CJC-1295 (without DAC) is a synthetic GHRH analog that stimulates the pituitary gland to release growth hormone (GH) in natural, pulsatile bursts. Unlike the DAC version (which provides a constant release), the no DAC form mimics natural GH rhythms, making it ideal for stacking with GHRP peptides for synergistic effects.Used in anti-aging, fat-loss, and recovery-focused protocols, CJC-1295 helps boost GH production without suppressing the body’s natural balance. When combined with GHRP-2, GHRP-6, or Ipamorelin, it amplifies growth hormone output and supports cell repair, deep sleep, metabolism, and tissue regeneration.

Key Benefits

Increases natural GH secretion in pulses
Enhances muscle repair, recovery, and fat loss
Supports deeper sleep and collagen synthesis
Best when stacked with GHRPs
Non-hormonal and well-tolerated

Scientific Background

CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH), designed to stimulate the pituitary gland to increase natural secretion of growth hormone (GH). Unlike native GHRH, CJC-1295 has been modified with a Drug Affinity Complex (DAC), which extends its half-life significantly—from minutes to more than 7 days—allowing for weekly rather than multiple daily injections.This extended activity makes CJC-1295 particularly valuable in protocols targeting fat loss, muscle growth, improved sleep, and anti-aging benefits, as it mimics the pulsatile GH release pattern, rather than overwhelming the system with exogenous GH.

What the Science Says: Summary of Key Studies

Long-Acting GH-Releasing Hormone Analogue in Humans

In a landmark clinical study by Teichman et al., healthy volunteers received subcutaneous injections of CJC-1295. The results showed:

A two- to ten-fold increase in mean GH levels for up to 6 days after a single injection.

A significant elevation of IGF-1 (Insulin-like Growth Factor 1) that lasted for up to 10 days.

No evidence of desensitization or pituitary suppression, even with repeated dosing.

Mechanism Behind the Long Half-Life - CJC-1295’s extended half-life is made possible by covalent binding to albumin, which protects it from enzymatic degradation and rapid renal clearance. This mechanism avoids frequent spikes and mimics a more physiological GH profile.

Synergy with GHRP-6 or Ipamorelin - Several animal and clinical studies suggest that combining CJC-1295 with growth hormone secretagogues (GHS) like GHRP-6 or Ipamorelin enhances the pulsatile GH release through dual receptor activation—one targeting the GHRH receptor, the other targeting the ghrelin receptor. This mimics natural GH pulses, with lower risk of desensitization.

By enhancing natural hormone function, CJC-1295 offers a regulated and more physiological path to performance and wellness—supported by both pharmacokinetics and clinical outcomes.

References

Reference: Teichman SL et al. (2006). Pharmacokinetics and pharmacodynamics of CJC-1295, a long-acting growth hormone releasing hormone analog, in healthy adults. J Clin Endocrinol Metab, 91(3):799-805. doi:10.1210/jc.2005-1536
Supported by: Frohman LA, et al. (2001). Novel peptidomimetics and analogs of GHRH. Endocr Rev, 22(6):768–780. doi:10.1210/er.22.6.768
Chen HY, et al. (2009). Ghrelin receptor agonists synergize with GHRH analogs. Peptides, 30(6):1026–1033. doi:10.1016/j.peptides.2009.01.018

Usage Instructions

Refer to the leaflet included with your product for detailed handling.

Reconstitute the lyophilized peptide with 1–2 ml bacteriostatic water, injecting slowly into the vial and swirling gently (do not shake).
Store reconstituted solution in the refrigerator (2–8 °C) and use within 10–14 days.
Administer via subcutaneous injection, preferably 30–60 minutes before bed or after training.
For best results, use on an empty stomach, and avoid carbs or fats around injection time to prevent GH blunting.

Dosage Information

Basic GH Optimization Protocol:

Dose: 100 mcg once or twice daily
Timing: Pre-bed or morning fasted
Use with: GHRP-2, GHRP-6, or Ipamorelin for max synergy

Performance or Recomposition Cycle:

Dose: 100 mcg 2–3× daily
Cycle Duration: 8–12 weeks

Stack with: IGF-1 LR3, GH mimetics, or fat-burning peptides

Anti-Aging Protocol:

Dose: 100 mcg once daily, pre-bed
Duration: Ongoing or in 8-week cycles

Important Warnings

For research use only – not approved for human therapeutic use
Store unreconstituted vials refrigerated (2–8 °C)
Use only bacteriostatic water to mix
After reconstitution, keep refrigerated and use within 10–14 days
Do not freezeUse sterile insulin syringes and rotate injection sites
Avoid use during illness or if experiencing abnormal pituitary symptoms
Discontinue if unexpected water retention, fatigue, or headaches occur

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What the Science Says: Summary of Key Studies

Long-Acting GH-Releasing Hormone Analogue in Humans

In a landmark clinical study by Teichman et al., healthy volunteers received subcutaneous injections of CJC-1295. The results showed:

A two- to ten-fold increase in mean GH levels for up to 6 days after a single injection.

A significant elevation of IGF-1 (Insulin-like Growth Factor 1) that lasted for up to 10 days.

No evidence of desensitization or pituitary suppression, even with repeated dosing.

By enhancing natural hormone function, CJC-1295 offers a regulated and more physiological path to performance and wellness—supported by both pharmacokinetics and clinical outcomes.

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