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Peptides Line

KPV

Name: KPV
Brand: Peptalon
SKU: PE-0017-01-5
Availability: InStock
Rating: 4.8 (127 reviews)

KPV is a powerful anti-inflammatory peptide that supports gut healing, immune balance, and skin health without suppressing the immune system.

From $48.00

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Key Ingredients

Lysine–Proline–Valine (KPV)

Anti inflammatory

Immune System Support

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

KPV is a short, naturally derived peptide fragment (Lysine–Proline–Valine) known for its powerful anti-inflammatory and immune-balancing effects. Unlike conventional treatments, it reduces inflammation without suppressing the immune system, making it ideal for chronic conditions.

What makes it unique?

KPV works locally and systemically to calm overactive immune responses, especially in the gut, skin, and soft tissue. It’s non-stimulant, non-hormonal, and does not cause pigmentation—making it a safe option for long-term use.

Who is it for?

KPV is suitable for individuals dealing with IBD, leaky gut, inflammatory skin conditions, or those looking to support immune health and recovery in a gentle, natural way.

Key Benefits:

Calms gut & skin inflammation
Supports immune balance
Non-hormonal & non-pigmenting
Safe for long-term use
No immunosuppression

Scientific Background

KPV is a tiny but powerful tripeptide made of three amino acids: lysine, proline, and valine. It was originally discovered as part of the larger hormone alpha-MSH, which helps regulate inflammation and immune responses. Researchers isolated KPV because it retained many of these anti-inflammatory properties but was much simpler and easier to use.What makes KPV fascinating is its ability to calm the immune system without shutting it down. It works by blocking inflammatory pathways like NF-κB, which are responsible for producing chemicals such as TNF-α and IL-6—key players in chronic inflammation. KPV has shown promise in treating skin inflammation, inflammatory bowel disease, and even post-injury swelling.Since it’s small, KPV can penetrate deep into tissues, making it a great option for topical or injectable therapies that target inflammation at the source, rather than relying on systemic medications like steroids.

References

Banno T, Gazel A, Blumenberg M. Effects of lysine-proline-valine (KPV) peptide on gene expression: Potential therapy for cutaneous inflammation. Exp Dermatol. 2004;13(2):129–136. https://doi.org/10.1111/j.0906-6705.2004.00135.x

Usage Instructions

To ensure safe and effective use of Peptide Products, like KPV, it’s important to follow correct preparation, handling, and injection techniques. Below is a summary of the most essential steps. For detailed guidance, please refer to the official Product Leaflet included with your vial. You can also view the the Leaflet online at the right bottom of the product page.

Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Suggested Dosage (Subcutaneous Use):

250–500 mcg daily, depending on severity of symptoms and treatment goals
In acute phases, up to 1 mg/day may be used short term
For gut or systemic inflammation, morning use is preferredFor skin issues, injection near affected area or topical use is ideal

Cycle Recommendation:

4–8 weeks, with breaks as needed
Safe for long-term or intermittent use depending on symptom recurrence

Important Warnings

Research compound: KPV is not approved as a pharmaceutical drug in most countries and should be used for research or educational purposes only, unless otherwise prescribed.
Allergic reactions: Though rare, monitor for signs such as rash, itching, or swelling at the application/injection site.
Immunomodulation: While KPV is anti-inflammatory, prolonged use might influence immune responses; avoid using it alongside systemic immunosuppressants unless under medical supervision.
Pregnancy & breastfeeding: Safety in pregnant or breastfeeding individuals has not been established—not recommended in these populations.
Storage: Keep KPV peptides refrigerated (2–8°C) and protect from light and moisture. Use reconstituted solution within recommended timeframe.

Frequently Asked Questions

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Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Suggested Dosage (Subcutaneous Use):

250–500 mcg daily, depending on severity of symptoms and treatment goals
In acute phases, up to 1 mg/day may be used short term
For gut or systemic inflammation, morning use is preferredFor skin issues, injection near affected area or topical use is ideal

Cycle Recommendation:

4–8 weeks, with breaks as needed
Safe for long-term or intermittent use depending on symptom recurrence

Important Warnings

Research compound: KPV is not approved as a pharmaceutical drug in most countries and should be used for research or educational purposes only, unless otherwise prescribed.
Allergic reactions: Though rare, monitor for signs such as rash, itching, or swelling at the application/injection site.
Immunomodulation: While KPV is anti-inflammatory, prolonged use might influence immune responses; avoid using it alongside systemic immunosuppressants unless under medical supervision.
Pregnancy & breastfeeding: Safety in pregnant or breastfeeding individuals has not been established—not recommended in these populations.
Storage: Keep KPV peptides refrigerated (2–8°C) and protect from light and moisture. Use reconstituted solution within recommended timeframe.

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