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Thymosin Alpha

Name: Thymosin Alpha
Brand: Peptalon
SKU: PE-0062-01-5
Availability: InStock
Rating: 4.8 (127 reviews)

Thymosin Alpha 1 (Tα1) is a bioactive peptide that helps regulate and enhance the immune system’s response to stress, infection, and inflammation.

From $54.00

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Key Ingredients

Thymosin Alpha 1

Anti inflammatory

Boost Recovery

Boosts Recovery

Safe and Natural

Not sure about the right dosage?

Use our Peptide Dosage Calculator for optimal application

Main Information

Thymosin Alpha 1 (Tα1) is a synthetic immune-regulating peptide that enhances the body’s defense against infections, inflammation, and immune imbalance. By activating T-cells and supporting immune coordination, it promotes resilience and recovery—without overstimulating the system. Tα1 is studied for its role in chronic infections, autoimmune modulation, and post-viral healing.

Best suited for: Individuals recovering from illness, managing low immune activity, or seeking preventive immune support during high-stress or high-risk periods. Key Benefits including:

Boosts immune cell activity (T-cells)
Supports post-viral and post-stress recovery
Helps regulate autoimmune responses
Non-stimulant, non-hormonal
Suitable for long-term immune support

Scientific Background

Thymosin Alpha-1 (Tα1) is a synthetic peptide modeled after a naturally occurring component of thymosin fraction 5, first isolated from calf thymus tissue in the 1970s by Dr. Allan Goldstein. Tα1 emerged as a lead compound for immune enhancement due to its ability to restore T-cell function in immunocompromised hosts. It has since been widely studied in the treatment of chronic infections, oncologic immunotherapy, and autoimmune modulation.Tα1 enhances innate and adaptive immunity by:

Promoting maturation and differentiation of T-lymphocytes
Increasing natural killer (NK) cell cytotoxicity
Upregulating MHC class I expression on antigen-presenting cells
Stimulating cytokine production (e.g., IL-2, IFN-γ)
Modulating Toll-like receptor (TLR) pathways to restore immune surveillance [1][2]

These effects make it particularly effective in states of immune exhaustion, such as viral persistence, chronic inflammation, or post-chemotherapy recovery.Tα1 has demonstrated protective effects against viral reactivation, sepsis, and even immune senescence, and is under investigation for its role in long-COVID protocols and biological resilience enhancement.Ideal for use in immune optimization, post-viral fatigue, autoimmune regulation, or burnout recovery in high-stress conditions.

References

Garaci E et al. Thymosin alpha1 in the treatment of cancer: from basic research to clinical application. Int J Immunopharmacol. 1995;17(9):683–688. doi: 10.1016/0192-0561(95)00045-d
Romani L et al. Thymosin alpha1 activates dendritic cells for antifungal Th1 resistance through Toll-like receptor signaling. Blood. 2004;103(11):4232–4239. doi: 10.1182/blood-2003-10-3635

Usage Instructions

To ensure safe and effective use of Peptide Products, like Thymosin Alpha, it’s important to follow correct preparation, handling, and injection techniques. Below is a summary of the most essential steps. For detailed guidance, please refer to the official Product Leaflet included with your vial. You can also view the the Leaflet online at the right bottom of the product page.

Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Dosage and frequency depend on individual needs, health goals, and application context. The following are commonly used research-based guidelines:

1. Immune Optimization / Preventive Use

Dosage: 1.0–1.5 mg once weekly
Use during high-stress periods, travel, or seasonal immune strain
Suitable for long-term immune resilience support

2. Post-Viral Recovery / Illness Support

Dosage: 1.5–2.0 mg twice weekly
Duration: 4–6 weeks
Supports recovery from viral infections, fatigue, or inflammation

3. Chronic Inflammation / Autoimmune Modulation

Dosage: 2.0 mg 2–3x per week
Duration: 6–12 weeks depending on symptom severity
Should be used under medical supervision or integrated into recovery protocols

Always start with the lowest effective dose, monitor immune response, and adjust as needed. For combination protocols (e.g., with LL-37 or Selank), consult a practitioner or protocol guide.

Important Warnings

Do not use in individuals with known hypersensitivity to thymosin-related peptides or any component of the formulation.
Not recommended during pregnancy or breastfeeding, unless explicitly prescribed under medical supervision.
Use with caution in patients with autoimmune conditions—Tα1 may modulate immune activity and should be considered case-by-case.
Individuals on immunosuppressive therapy (e.g. post-transplant or chemotherapy) should consult a healthcare provider before use.
Clinical data on long-term use in healthy populations is limited; intermittent protocols are preferred.
Minor side effects may include fatigue, local redness or swelling at the injection site, or transient flu-like symptoms, particularly during the first few doses.
n rare cases, Tα1 may interact with cytokine-modulating therapies or interfere with immunological test results—monitor accordingly in clinical settings.
Always administer using sterile technique, and store the product refrigerated at 2–8 °C. Do not use if solution appears cloudy or discolored.
Keep out of reach of children. Intended for advanced wellness use under supervision.Store lyophilized vial refrigerated (2–8 °C).

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Inspect the solution before each use by gently tipping or swirling the vial or preloaded syringe once or twice.
Do not use if the solution appears cloudy, discolored, or contains particles.
Peptide products are typically supplied as a lyophilized (freeze-dried) powder.
Reconstitute using bacteriostatic water.
Inject slowly along the vial wall and swirl gently (do not shake) until fully dissolved and clear.
This peptide is intended for subcutaneous injection using insulin syringes (up to 16 mm needle length).
Always use a new, sterile syringe and needle for every injection.
Maintain aseptic technique and never reuse syringes.
Rotate the injection sites (e.g., abdomen, thighs, or upper arm) to avoid local irritation or tissue damage.
Before injecting, check that the syringe is correctly loaded: a small drop of solution should appear at the needle tip. If not, discard the syringe and prepare a new one.
Refer to sections E–G on pages 10–11 of the Product Leaflet for visual instruction, if available.
Store the lyophilized powder refrigerated at 2–8 °C.
After reconstitution, use within 7–14 days, keeping the solution refrigerated.
Do not freeze. Protect from light.

Dosage Information

Dosage and frequency depend on individual needs, health goals, and application context. The following are commonly used research-based guidelines:

1. Immune Optimization / Preventive Use

Dosage: 1.0–1.5 mg once weekly
Use during high-stress periods, travel, or seasonal immune strain
Suitable for long-term immune resilience support

2. Post-Viral Recovery / Illness Support

Dosage: 1.5–2.0 mg twice weekly
Duration: 4–6 weeks
Supports recovery from viral infections, fatigue, or inflammation

3. Chronic Inflammation / Autoimmune Modulation

Dosage: 2.0 mg 2–3x per week
Duration: 6–12 weeks depending on symptom severity
Should be used under medical supervision or integrated into recovery protocols

Always start with the lowest effective dose, monitor immune response, and adjust as needed. For combination protocols (e.g., with LL-37 or Selank), consult a practitioner or protocol guide.

Important Warnings

Do not use in individuals with known hypersensitivity to thymosin-related peptides or any component of the formulation.
Not recommended during pregnancy or breastfeeding, unless explicitly prescribed under medical supervision.
Use with caution in patients with autoimmune conditions—Tα1 may modulate immune activity and should be considered case-by-case.
Individuals on immunosuppressive therapy (e.g. post-transplant or chemotherapy) should consult a healthcare provider before use.
Clinical data on long-term use in healthy populations is limited; intermittent protocols are preferred.
Minor side effects may include fatigue, local redness or swelling at the injection site, or transient flu-like symptoms, particularly during the first few doses.
n rare cases, Tα1 may interact with cytokine-modulating therapies or interfere with immunological test results—monitor accordingly in clinical settings.
Always administer using sterile technique, and store the product refrigerated at 2–8 °C. Do not use if solution appears cloudy or discolored.
Keep out of reach of children. Intended for advanced wellness use under supervision.Store lyophilized vial refrigerated (2–8 °C).

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